4(Z-3-chloroallyl)benzaldehyde → 4(Z-3-chloroallyl)benzyl alcohol
반응식
[Cl:1]/[CH:2]=[CH:3]\[CH2:4][C:5]1[CH:12]=[CH:11][C:8]([CH:9]=[O:10])=[CH:7][CH:6]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>CCOCC>[Cl:1]/[CH:2]=[CH:3]\[CH2:4][C:5]1[CH:12]=[CH:11][C:8]([CH2:9][OH:10])=[CH:7][CH:6]=1참가 물질
4
실험 절차
The aldehyde (0.22 g) of Example 1 in ether (5 ml) is added to lithium aluminum hydride (0.08 g) in ether (5 ml), and the mixture stirred at 20° for 1 hour. After successive dropwise additions of water (80 l), 15% NaOH (80 l) and water (240 l), the resulting clear ether layer (+ washings) is evaporated to a residue of 4(Z-3-chloroallyl)benzyl alcohol yield 0.19 g (86%) nD25 1.5529.
후처리
- customAfter successive dropwise additions of water (80 l), 15% NaOH (80 l) and water (240 l), the resulting clear ether layer (+ washings) is evaporated to a residue of 4(Z-3-chloroallyl)benzyl alcohol yield 0.19 g (86%) nD25 1.5529
출처 및 근거
- ORD 기록
- ord-c30f7967b9d54af88e44e5ecba3d2c59
- 출처 데이터셋
- uspto-grants-1987_05
- 특허 번호
- US04668701
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