6-Bromo-4-{4-[4-(methylsulfonyl)phenoxy]piperidino}quinoline → 4-[4-(4-methylsulfonylphenoxy)piperidin-1-yl]-6-(1-trityl-1H-pyrazol-4-yl) quinoline

반응식

[Br:1][c:2]1[cH:3][c:4]2[c:5]([N:12]3[CH2:13][CH2:14][CH:15]([O:18][c:19]4[cH:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[CH3:28])[cH:23][cH:24]4)[CH2:16][CH2:17]3)[cH:6][cH:7][n:8][c:9]2[cH:10][cH:11]1.[C:29]([c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1)([c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1)([c:42]1[cH:43][cH:44][cH:45][cH:46][cH:47]1)[n:48]1[n:49][cH:50][c:51]([B:53]([OH:54])[OH:55])[cH:52]1>>[c:2]1(-[c:51]2[cH:50][n:49][n:48]([C:29]([c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)([c:36]3[cH:37][cH:38][cH:39][cH:40][cH:41]3)[c:42]3[cH:43][cH:44][cH:45][cH:46][cH:47]3)[cH:52]2)[cH:3][c:4]2[c:5]([N:12]3[CH2:13][CH2:14][CH:15]([O:18][c:19]4[cH:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[CH3:28])[cH:23][cH:24]4)[CH2:16][CH2:17]3)[cH:6][cH:7][n:8][c:9]2[cH:10][cH:11]1

참가 물질

반응물 2

HCID 220311826-Bromo-4-{4-[4-(methylsulfonyl)phenoxy]piperidino}quinoline

HCID 22031737(1-Trityl-1H-pyrazol-4-yl)boronic acid

생성물 1

HCID 688153364-[4-(4-methylsulfonylphenoxy)piperidin-1-yl]-6-(1-trityl-1H-pyrazol-4-yl) quinoline

출처 및 근거

ORD 기록: ord-9fe6e26369b046178eb080ca19347ffe
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…