Thionyl Chloride → HCID 178444488, 화합물

HRID 980424노트

반응식

HRID 980424 반응식
[CH2:1]([C@H:6]1[CH2:11][CH2:10][C@H:9]([CH2:12][C:13]([OH:15])=O)[CH2:8][CH2:7]1)[CH2:2][CH2:3][CH2:4][CH3:5].S(Cl)([Cl:18])=O>>[CH2:1]([C@H:6]1[CH2:11][CH2:10][C@H:9]([CH2:12][C:13]([Cl:18])=[O:15])[CH2:8][CH2:7]1)[CH2:2][CH2:3][CH2:4][CH3:5]

참가 물질

3

반응물 2

HCID 24386Thionyl ChlorideHCID 178444491HCID 178444491, 화합물

생성물 1

HCID 178444488HCID 178444488, 화합물

실험 절차

For conversion into the acid chloride, trans-4-pentylcyclohexylacetic acid (12.0 g, 0.0566 mol) was reacted for about 1 hour on an oil bath at 80° C. with thionyl chloride (50 ml). The solution obtained was evaporated under reduced pressure, treated with absolute toluene (50 ml) and once more evaporated under reduced pressure.

후처리

  1. customThe solution obtained
  2. customwas evaporated under reduced pressure
  3. additiontreated with absolute toluene (50 ml)
  4. customonce more evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-f5c682759cb14903a7140f0f7b826a0a
출처 데이터셋
uspto-grants-1987_01
특허 번호
US04637897

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