1H-Imidazole-4,5-dicarboxylic acid → Cholesterol 5alpha,6alpha-Epoxide alpha,beta-Imidazole Dicarboxylic Acid

HRID 980789노트

반응식

HRID 980789 반응식
[CH3:1][C@@H:2]([C@@H:9]1[C@@:13]2([CH3:29])[CH2:14][CH2:15][C@@H:16]3[C@@:21]4([CH3:27])[CH2:22][CH2:23][C@H:24]([OH:26])[CH2:25][C@:20]54[O:28][C@H:19]5[CH2:18][C@H:17]3[C@@H:12]2[CH2:11][CH2:10]1)[CH2:3][CH2:4][CH2:5][CH:6]([CH3:8])[CH3:7].[CH:30]1[NH:34][C:33]([C:35]([OH:37])=[O:36])=[C:32]([C:38]([OH:40])=[O:39])[N:31]=1>>[CH3:1][C@@H:2]([C@@H:9]1[C@@:13]2([CH3:29])[CH2:14][CH2:15][C@@H:16]3[C@@:21]4([CH3:27])[CH2:22][CH2:23][C@H:24]([OH:26])[CH2:25][C@:20]54[O:28][C@H:19]5[CH2:18][C@H:17]3[C@@H:12]2[CH2:11][CH2:10]1)[CH2:3][CH2:4][CH2:5][CH:6]([CH3:7])[CH3:8].[CH:30]1[NH:31][C:32]([C:38]([OH:40])=[O:39])=[C:33]([C:35]([OH:37])=[O:36])[N:34]=1

참가 물질

3

반응물 2

HCID 684421H-Imidazole-4,5-dicarboxylic acidHCID 2270375alpha,6alpha-Epoxycholesterol

생성물 1

HCID 131715038Cholesterol 5alpha,6alpha-Epoxide alpha,beta-Imidazole Dicarboxylic Acid

실험 절차

Following the procedure of Example 29 cholesterol 5α,6α-epoxide and α,β-imidazole dicarboxylic acid in 1:2 molar ratio under alkaline conditions produce the desired product. ##STR10##

출처 및 근거

ORD 기록
ord-be8c848a050946f7aa1dac4eb23c174d
출처 데이터셋
uspto-grants-1987_01
특허 번호
US04639420

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