Acetic Acid → Dimethylmaleic anhydride

HRID 980921

반응식

HRID 980921 반응식
C1(=O)O[C:4](=[O:5])[CH:3]=[CH:2]1.O.O.O.[C:11]([O-:14])(=[O:13])[CH3:12].[Na+].[C:16](O)(=O)C>C1(NC2C=CC=CN=2)C=CC=CC=1>[CH3:2][C:3]1=[C:12]([CH3:16])[C:11]([O:14][C:4]1=[O:5])=[O:13]

참가 물질

5

반응물 3

HCID 176Acetic Acid2회HCID 7923Maleic AnhydrideHCID 23665404Sodium Acetate Trihydrate

생성물 1

HCID 13010Dimethylmaleic anhydride수율 44.3%

시약·촉매·용매 1

HCID 81130N-2-Pyridylaniline촉매

실험 절차

A solution of 98.0 g (1 mol) of maleic anhydride in 200 ml of glacial acetic acid is added dropwise over 1 hour to a boiling mixture of 1.7 g (0.01 mol) of 2-phenylaminopyridine and 22.8 g of sodium acetate trihydrate in 100 ml of glacial acetic acid. The mixture is subsequently boiled under reflux for 18 hours. Working up as in Example 1 affords 27.9 g (44.3%) of dimethylmaleic anhydride with a melting point of 91°-93° C.

후처리

  1. temperatureunder reflux for 18 hours

출처 및 근거

ORD 기록
ord-49e60844a8f64f8d865b5f062b4a5e7f
출처 데이터셋
uspto-grants-1987_01
특허 번호
US04639531

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