Boron, trifluoro(methanol)-, (T-4)- → Methyl 2-(3-methoxyphenyl)-5-oxo-1-phenylpyrrolidin-3-carboxylate

HRID 980934

반응식

HRID 980934 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]2[CH:13]([C:14]([OH:16])=[O:15])[CH2:12][C:11](=[O:17])[N:10]2[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:6]=[CH:7][CH:8]=1.B(F)(F)F.[CH3:28]O>>[CH3:28][O:15][C:14]([CH:13]1[CH2:12][C:11](=[O:17])[N:10]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:9]1[C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=1)=[O:16]

참가 물질

3

반응물 2

HCID 11062313Boron, trifluoro(methanol)-, (T-4)-HCID 133619852-(3-Methoxyphenyl)-5-oxo-1-phenylpyrrolidin-3-carboxylic acid

생성물 1

HCID 13362002Methyl 2-(3-methoxyphenyl)-5-oxo-1-phenylpyrrolidin-3-carboxylate

실험 절차

A solution of 25.0 gm. of 2-(3-methoxyphenyl)-5-oxo-1-phenylpyrrolidin-3-carboxylic acid in 200 ml 10-15% boron fluoride-methanol was refluxed for 8 hours and upon following the workup for example 1C the product was obtained as an oil.

후처리

  1. customwas obtained as an oil

출처 및 근거

ORD 기록
ord-547bbf377ac84c26a22b0895622c04ce
출처 데이터셋
uspto-grants-1987_01
특허 번호
US04639529

연결된 노트

불러오는 중…