1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazine → N-(2,6-dimethylphenyl)-1-[4-(4-fluorophenyl)methylphenyl]-4-piperazinacetamide

HRID 981

반응식

HRID 981 반응식
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[NH:9][C:10](=[O:13])[CH2:11]Br.[F:14][C:15]1[CH:20]=[CH:19][C:18]([CH2:21][C:22]2[CH:27]=[CH:26][C:25]([N:28]3[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]3)=[CH:24][CH:23]=2)=[CH:17][CH:16]=1>>[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[NH:9][C:10](=[O:13])[CH2:11][N:31]1[CH2:30][CH2:29][N:28]([C:25]2[CH:24]=[CH:23][C:22]([CH2:21][C:18]3[CH:19]=[CH:20][C:15]([F:14])=[CH:16][CH:17]=3)=[CH:27][CH:26]=2)[CH2:33][CH2:32]1

참가 물질

3

반응물 2

HCID 15199981-[4-[(4-Fluorophenyl)methyl]phenyl]piperazineHCID 27634872-bromo-N-(2,6-dimethylphenyl)acetamide

생성물 1

HCID 19694242N-(2,6-dimethylphenyl)-1-[4-(4-fluorophenyl)methylphenyl]-4-piperazinacetamide

실험 절차

The compound (18) synthesized in Reference Example 18 and the compound (5) synthesized in Reference Example 5 were used to produce the above compound in the same way as Example 1.

후처리

  1. customto produce the above compound in the same way as Example 1

출처 및 근거

ORD 기록
ord-63ce7425d0de4ff99768647be804a6c5
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05723475

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