HCID 20071767, 화합물 → HCID 20071746, 화합물
반응식
FC(F)(F)C(OC[S:7][C:8]1[CH:13]=[CH:12][C:11]([C:14](=[O:22])[CH:15]([CH3:21])[CH2:16][C:17]([O:19][CH3:20])=[O:18])=[CH:10][CH:9]=1)=O>CO.CCN(CC)CC>[SH:7][C:8]1[CH:9]=[CH:10][C:11]([C:14](=[O:22])[CH:15]([CH3:21])[CH2:16][C:17]([O:19][CH3:20])=[O:18])=[CH:12][CH:13]=1참가 물질
3
실험 절차
To the neat trifluoroacetate from Step D of this Example (12.3 g) was added a mixture of 1:1 MeOH-NEt3 (600 ml) and the resulting reaction mixture was evaporated under vacuum. The procedure was repeated twice more. The residue was dissolved in CH2Cl2, washed with 1N HCl and brine and dried over Na2SO4. Evaporation of the solvent gave the title compound as an oil (7.8 g, 97%).
후처리
- customthe resulting reaction mixture
- customwas evaporated under vacuum
- dissolutionThe residue was dissolved in CH2Cl2
- washwashed with 1N HCl and brine
- dry with materialdried over Na2SO4
- customEvaporation of the solvent
출처 및 근거
- ORD 기록
- ord-e46a4b2c1164441c8755e73ac85dd5ea
- 출처 데이터셋
- uspto-grants-1991_02
- 특허 번호
- US04990526
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