Ethanol → HCID 14646898, 화합물

HRID 981350

반응식

HRID 981350 반응식
[OH-:1].[K+].[CH2:3]([OH:5])[CH3:4].[SH:6][C:7]1[S:8][C:9]([SH:12])=[N:10][N:11]=1.Br[CH:14]([CH2:18][C:19]([OH:21])=[O:20])[C:15]([OH:17])=[O:16]>O>[S:8]1[C:9]([S:12][CH:4]([CH2:14][C:15]([OH:17])=[O:16])[C:3]([OH:1])=[O:5])=[N:10][N:11]=[C:7]1[S:6][CH:14]([CH2:18][C:19]([OH:21])=[O:20])[C:15]([OH:17])=[O:16]

참가 물질

6

반응물 4

HCID 702Ethanol4회HCID 14797Potassium Hydroxide2회HCID 73557Bromosuccinic acidHCID 178418558HCID 178418558, 화합물

생성물 1

HCID 14646898HCID 14646898, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

About 68 g. of a solution of 39.6 g. (0.6 mole) of KOH (85%) in 200 ml. of abs. ethanol is added to a stirred slurry of 15.0 g. (0.1 mole) of 2,5-dimercapto-1,3,4-thiadiazole in 80 ml. of abs. ethanol, at 10°-15° C. The resultant mixture is stirred at 10°-15° C. for half hour thereafter, a clear solution of 39.4 g. (0.2 mole) of bromosuccinic acid in 70 ml. of abs. ethanol is added dropwise over a period of 15 minutes at 10°-15° C. followed by the gradual addition of the remainder of the KOH solution at the same temperature range over a period of 15 minutes. After adding 100 ml. of abs. ethanol, the reaction mixture is stirred in the cooling bath for more than one hour, then overnight in water bath at ambient temperature.

후처리

  1. customat 10°-15° C
  2. additionAfter adding 100 ml
  3. customat ambient temperature

출처 및 근거

ORD 기록
ord-4d86d0665c834e09a920b9983f2b6ec4
출처 데이터셋
uspto-grants-1991_02
특허 번호
US04990652

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