Phenol, 2,6-bis(1,1-dimethylethyl)-4-nitroso- → 4-Amino-2,6-di-tert-butylphenol

HRID 981374

반응식

HRID 981374 반응식
[C:1]([C:5]1[CH:10]=[C:9]([N:11]=O)[CH:8]=[C:7]([C:13]([CH3:16])([CH3:15])[CH3:14])[C:6]=1[OH:17])([CH3:4])([CH3:3])[CH3:2]>[Pd].C1(C)C=CC=CC=1>[C:1]([C:5]1[CH:10]=[C:9]([NH2:11])[CH:8]=[C:7]([C:13]([CH3:16])([CH3:15])[CH3:14])[C:6]=1[OH:17])([CH3:4])([CH3:3])[CH3:2]

참가 물질

4

반응물 1

HCID 70383Phenol, 2,6-bis(1,1-dimethylethyl)-4-nitroso-

생성물 1

HCID 3142204-Amino-2,6-di-tert-butylphenol

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 1140Toluene용매

실험 절차

A 2 liter Parr bomb was charged with 23.50 g (0.1 mole) 2,6-di-tert-butyl-4-nitrosophenol, 1.0 g of 5% Pd on C catalyst and 600 ml toluene. After purging the assembled bomb with nitrogen, it was pressurized to 50 psi with hydrogen. The mixture was stirred vigorously and uptake of hydrogen was noted. The hydrogenation step producing 2,6-di-tert-butyl-4-aminophenol was completed within 15 minutes. A temperature rise from 23° C. to 25° C. was observed during the hydrogenation. The mixture was allowed to stir under hydrogen atmosphere for a total of 1 hour.

후처리

  1. customAfter purging the assembled bomb with nitrogen, it

출처 및 근거

ORD 기록
ord-da1b63cbfb004957b00349c2a1e3c2e1
출처 데이터셋
uspto-grants-1991_02
특허 번호
US04990671

연결된 노트

불러오는 중…