1-Ethyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → HCID 18643684, 화합물
반응식
[CH2:1]([N:3]1[C:12]2[C:7](=[CH:8][C:9]([F:14])=[C:10](F)[CH:11]=2)[C:6](=[O:15])[C:5]([C:16]([OH:18])=[O:17])=[CH:4]1)[CH3:2].[NH2:19][C@@H:20]1[CH2:22][C@@H:21]1[NH2:23]>N1C=CC=CC=1>[NH2:19][C@H:20]1[CH2:22][C@H:21]1[NH:23][C:10]1[CH:11]=[C:12]2[C:7]([C:6](=[O:15])[C:5]([C:16]([OH:18])=[O:17])=[CH:4][N:3]2[CH2:1][CH3:2])=[CH:8][C:9]=1[F:14]참가 물질
4
실험 절차
A mixture of 1-ethyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid and cis 1,2-diamino cyclopropane [Synthetic Communications, 11(6), 493-495 (1981)] in pyridine is reacted as described in Example 1 giving the desired product.
후처리
- customis reacted
출처 및 근거
- ORD 기록
- ord-c972d5ec153a411ab098aaaa2538578c
- 출처 데이터셋
- uspto-grants-1991_02
- 특허 번호
- US04992449
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