Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,4-dihydro-2H-pyran → 2H-Pyran, 2-(4-chlorobutoxy)tetrahydro-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,4-dihydro-2H-pyran | HCID 8080 | — |
| 반응물 | 4-Chloro-1-butanol | HCID 13569 | — |
| 촉매 | Hydrochloric Acid | HCID 313 | — |
| 생성물 | 2H-Pyran, 2-(4-chlorobutoxy)tetrahydro- | HCID 170488 | 89.9% |
반응 단계
Dihydropyran (15.5 g) was added dropwise to a mixture of 4-chlorobutanol (20 g) and hydrochloric acid (18M, 1 drop) at RT. The mixture was stirred for 30 min and washed with H2O (100 ml), aqueous NaHCO3 (1M, 50 ml) and BR (50 ml). The dried liquid was heated under reduced pressure to leave the title compound as a colourless liquid (31.9 g). T.l.c. [L] Rf 0.5.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04992474 |
| 출처 데이터셋 | uspto-grants-1991_02 |
| ORD ID | ord-b0a14c328c734266849ffc9d04757122 |
| 출처 메모 | uspto-grants-1991_02 |