3-Chloro-6-cyclopentyl-6-[4-(3-hydroxy-phenyl)-but-3-ynyl]-dihydro-pyran-2,4-dione → N-{2-[2-Cyclopentyl-5-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylsulfanyl)-4-hydroxy-6-oxo-3,6-dihydro-2H-pyran-2-yl]-ethyl}-3-furan-2-yl-propionamide

반응식

[CH3:52][c:53]1[n:54][c:55]2[n:56]([c:57]([CH3:59])[cH:58]1)[n:60][c:61]([SH:63])[n:62]2.[Cl:1][CH:2]1[C:3](=[O:26])[CH2:4][C:5]([CH:9]2[CH2:10][CH2:11][CH2:12][CH2:13]2)([CH2:14][CH2:15][NH:16][C:17]([CH2:18][CH2:19][c:20]2[o:21][cH:22][cH:23][cH:24]2)=[O:25])[O:6][C:7]1=[O:8].[Cl:27][CH:28]1[C:29](=[O:30])[CH2:31][C:32]([CH:33]2[CH2:34][CH2:35][CH2:36][CH2:37]2)([CH2:38][CH2:39][C:40]#[C:41][c:42]2[cH:43][cH:44][cH:45][c:46]([OH:47])[cH:48]2)[O:49][C:50]1=[O:51]>>[C:2]1([S:63][c:61]2[n:60][n:56]3[c:55]([n:54][c:53]([CH3:52])[cH:58][c:57]3[CH3:59])[n:62]2)=[C:3]([OH:26])[CH2:4][C:5]([CH:9]2[CH2:10][CH2:11][CH2:12][CH2:13]2)([CH2:14][CH2:15][NH:16][C:17]([CH2:18][CH2:19][c:20]2[o:21][cH:22][cH:23][cH:24]2)=[O:25])[O:6][C:7]1=[O:8]