Ammonia → HCID 20071066, 화합물

HRID 981815노트

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HRID 981815 반응식
Cl[C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4]([NH:9][CH3:10])[C:3]=1[N+:11]([O-:13])=[O:12].[NH3:14]>O.C(O)C>[Cl:8][C:6]1[CH:5]=[C:4]([NH:9][CH3:10])[C:3]([N+:11]([O-:13])=[O:12])=[C:2]([NH2:14])[CH:7]=1

참가 물질

5

반응물 2

HCID 222AmmoniaHCID 20071071HCID 20071071, 화합물

생성물 1

HCID 20071066HCID 20071066, 화합물

시약·촉매·용매 2

HCID 702Ethanol용매HCID 962Water용매

실험 절차

0.034 mole (7.5 g) of 2,4-dichloro-6-methylaminonitrobenzene is added in an autoclave to 100 ml of a 28% strength solution of ammonia in water and 50 ml of ethanol. The reaction mixture is heated to 145°-150° C. for 12 hours, the pressure being 12 kg/cm2. After cooling, the expected product precipitates from the reaction mixture. After being filtered off and reslurried in water, it is dried hot under vacuum in the presence of phosphorus pentoxide. Recrystallized from isopropanol, it melts at 129° C.

후처리

  1. temperatureThe reaction mixture is heated to 145°-150° C. for 12 hours
  2. temperatureAfter cooling
  3. customthe expected product precipitates from the reaction mixture
  4. filtrationAfter being filtered off
  5. dry with materialit is dried hot under vacuum in the presence of phosphorus pentoxide
  6. customRecrystallized from isopropanol, it melts at 129° C.

출처 및 근거

ORD 기록
ord-83c131031f14438284faf397fa7f4eb6
출처 데이터셋
uspto-grants-1991_02
특허 번호
US04992586

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