3-Chloroacetylpyridine → (1S)-2-(methylamino)-1-pyridin-3-ylethanol

HRID 982734

반응식

[CH3:1][NH:2]C[C@H](C1C=CC=CN=1)O.Cl[CH2:13][C:14]([C:16]1[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=1)=[O:15]>>[CH3:1][NH:2][CH2:13][C@H:14]([C:16]1[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=1)[OH:15]

참가 물질

반응물 2

HCID 4162523-Chloroacetylpyridine

HCID 10149007(R)-2-(methylamino)-1-pyridin-2-ylethanol

생성물 1

HCID 10171254(1S)-2-(methylamino)-1-pyridin-3-ylethanol

실험 절차

As described for the preparation of (1R)-2-(methylamino)-1-pyridin-2-ylethanol (Preparations 27-28), 3-chloroacetylpyridine (Chem. Ber. 1951, 84, 147-149) is converted to the title compound, isolated as a pale yellow amorphous solid.

출처 및 근거

ORD 기록: ord-67e4a5371e76474ab01f2d2f05bc0b35
출처 데이터셋: uspto-grants-2005_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06861438B2

연결된 노트

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