Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethanolamine → 4-[3-[N,N-bis(2-hydroxyethyl)amino]propyl]-2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-2H-pyridazin-3-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethanolamine | HCID 8113 | — |
| 반응물 | 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-(3-metha nesulfonyloxypropyl)-2H-pyridazin-3-one | HCID 21991559 | — |
| 생성물 | 4-[3-[N,N-bis(2-hydroxyethyl)amino]propyl]-2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-2H-pyridazin-3-one | HCID 21991397 | 13.1% |
반응 단계
Following the procedure of Example 1(10), 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-(3-methanesulfonyloxypropyl)-2H-pyridazin-3-one and diethanolamine were reacted to yield the title compound as a yellow oil (yield: 13.1%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06861428B2 |
| 출처 데이터셋 | uspto-grants-2005_03 |
| ORD ID | ord-a8e7b89f91004496a4d9ba1ec2b74b07 |
| 출처 메모 | uspto-grants-2005_03 |