Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,4-Difluorobenzyl Chloride → 4-carboxy-2-(3,4-difluorobenzyl)-6-(4-fluoro-3-methylphenyl)-2H-pyridazin-3-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,4-Difluorobenzyl Chloride | HCID 2736954 | — |
| 반응물 | 6-(4-fluoro-3-methylphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one | HCID 21991459 | — |
| 생성물 | 4-carboxy-2-(3,4-difluorobenzyl)-6-(4-fluoro-3-methylphenyl)-2H-pyridazin-3-one | HCID 22562308 | 66.7% |
반응 단계
Following the procedure of Example 1(6), 6-(4-fluoro-3-methylphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one and 3,4-difluorobenzyl chloride were reacted. Without purification, the reaction product was reacted further following the procedure of Example 1(7) to yield the title compound as a pale yellow solid (yield: 66.7%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06861428B2 |
| 출처 데이터셋 | uspto-grants-2005_03 |
| ORD ID | ord-6e924e461c0c4b41ac1a9932e726075d |
| 출처 메모 | uspto-grants-2005_03 |