Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl Ether → 2,4-Dichlorobenzylidenemalononitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl Ether | HCID 3283 | — |
| 반응물 | Malononitrile | HCID 8010 | — |
| 반응물 | 2,4-Dichlorobenzaldehyde | HCID 13404 | — |
| 촉매 | Piperidine | HCID 8082 | — |
| 용매 | 1-Butanol | HCID 263 | — |
| 생성물 | 2,4-Dichlorobenzylidenemalononitrile | HCID 18089 | — |
반응 단계
Under an atmosphere of argon, 2,4-dichlorobenzaldehyde (30.00 g, 171 mmol) and malononitrile (13.59 g, 206 mmol) were suspended in 1-butanol (350 ml). After stirring for 15 min, 8 drops of piperidine were added at room temperature. After stirring for an additional 3 h, diethyl ether was added. The precipitate was filtered and washed with diethyl ether and hexane to give the title compound, MS: m/e=222.8 (M+), as a colorless solid (35.34 g, 92%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06867205B2 |
| 출처 데이터셋 | uspto-grants-2005_03 |
| ORD ID | ord-5500adcfe11f4975895e20aa0422a449 |
| 출처 메모 | uspto-grants-2005_03 |