6-trifluoromethyl-1H-indol-3-yl-acetamide → 3-(6,6-dimethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(6-trifluoromethyl-1H-indol-3-yl)pyrrole-2,5-dione
반응식
[F:1][C:2]([F:17])([F:16])[C:3]1[CH:11]=[C:10]2[C:6]([C:7]([CH2:12][C:13]([NH2:15])=[O:14])=[CH:8][NH:9]2)=[CH:5][CH:4]=1.C[O:19][C:20](=O)[C:21]([C:23]1[C:33]2=[C:34]3[C:29](=[CH:30][CH:31]=[CH:32]2)[C:28]([CH3:36])([CH3:35])[CH2:27][CH2:26][N:25]3[CH:24]=1)=O>>[CH3:35][C:28]1([CH3:36])[C:29]2[C:34]3=[C:33]([C:23]([C:21]4[C:20](=[O:19])[NH:15][C:13](=[O:14])[C:12]=4[C:7]4[C:6]5[C:10](=[CH:11][C:3]([C:2]([F:16])([F:1])[F:17])=[CH:4][CH:5]=5)[NH:9][CH:8]=4)=[CH:24][N:25]3[CH2:26][CH2:27]1)[CH:32]=[CH:31][CH:30]=2참가 물질
3
실험 절차
Beginning with (6-(trifluoromethyl)indol-3-yl)acetamide and (6,6-dimethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)oxoacetic acid methyl ester, the title compound was prepared essentially as described in Example 1.
출처 및 근거
- ORD 기록
- ord-deaca3a3ab234fe39bbbc0319e46d7dd