6-trifluoromethyl-1H-indol-3-yl-acetamide → 3-(5-Hydroxymethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(6-trifluoromethyl-1H-indol-3-yl)-pyrrolidine-2,5-dione
반응식
C[O:2][C:3](=O)[C:4]([C:6]1[C:16]2=[C:17]3[C:12](=[CH:13][CH:14]=[CH:15]2)[CH2:11][CH:10]([CH2:18][OH:19])[CH2:9][N:8]3[CH:7]=1)=O.[F:21][C:22]([F:37])([F:36])[C:23]1[CH:31]=[C:30]2[C:26]([C:27]([CH2:32][C:33]([NH2:35])=[O:34])=[CH:28][NH:29]2)=[CH:25][CH:24]=1>>[OH:19][CH2:18][CH:10]1[CH2:11][C:12]2[C:17]3=[C:16]([C:6]([CH:4]4[CH:32]([C:27]5[C:26]6[C:30](=[CH:31][C:23]([C:22]([F:36])([F:21])[F:37])=[CH:24][CH:25]=6)[NH:29][CH:28]=5)[C:33](=[O:34])[NH:35][C:3]4=[O:2])=[CH:7][N:8]3[CH2:9]1)[CH:15]=[CH:14][CH:13]=2참가 물질
3
반응물 2
생성물 1
실험 절차
Beginning with (5-(hydroxymethyl)-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl]oxo-acetic acid methyl ester and (6-(trifluoromethyl)-1H-indol-3-yl)acetamide, the title compound was prepared essentially as described in Example 1.
출처 및 근거
- ORD 기록
- ord-a27baa075f534926894bee36b41186a9