2-(6-Methoxy-1H-indol-3-yl)acetamide → 3-(5-Hydroxymethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(6-methoxy-1H-indol-3-yl)-pyrrolidine-2,5-dione
반응식
C[O:2][C:3](=O)[C:4]([C:6]1[C:16]2=[C:17]3[C:12](=[CH:13][CH:14]=[CH:15]2)[CH2:11][CH:10]([CH2:18][O:19][Si](C(C)(C)C)(C)C)[CH2:9][N:8]3[CH:7]=1)=O.[CH3:28][O:29][C:30]1[CH:38]=[C:37]2[C:33]([C:34]([CH2:39][C:40]([NH2:42])=[O:41])=[CH:35][NH:36]2)=[CH:32][CH:31]=1>>[OH:19][CH2:18][CH:10]1[CH2:11][C:12]2[C:17]3=[C:16]([C:6]([CH:4]4[CH:39]([C:34]5[C:33]6[C:37](=[CH:38][C:30]([O:29][CH3:28])=[CH:31][CH:32]=6)[NH:36][CH:35]=5)[C:40](=[O:41])[NH:42][C:3]4=[O:2])=[CH:7][N:8]3[CH2:9]1)[CH:15]=[CH:14][CH:13]=2참가 물질
3
반응물 2
생성물 1
실험 절차
Beginning with (5-(tert-butyldimethylsilyloxymethyl)-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl]oxoacetic acid methyl ester and (6-methoxy-1H-indol-3-yl)acetamide, the title compound was prepared essentially as described in Example 1.
출처 및 근거
- ORD 기록