2-(6-fluoro-1H-indol-3-yl)acetamide → 3-(6-Fluoro-1H-indol-3-yl)-4-(4-hydroxylmethyl-5,6-dihydro-4H-pyrrolo[3,2, 1-ij]quinolin-1-yl)pyrrole-2,5-dione
반응식
[F:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH2:11][C:12]([NH2:14])=[O:13])=[CH:7][NH:8]2)=[CH:4][CH:3]=1.C[O:16][C:17](=O)[C:18]([C:20]1[C:30]2=[C:31]3[C:26](=[CH:27][CH:28]=[CH:29]2)[CH2:25][CH2:24][CH:23]([CH2:32][OH:33])[N:22]3[CH:21]=1)=O>>[F:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:11]3[C:12](=[O:13])[NH:14][C:17](=[O:16])[C:18]=3[C:20]3[C:30]4=[C:31]5[C:26](=[CH:27][CH:28]=[CH:29]4)[CH2:25][CH2:24][CH:23]([CH2:32][OH:33])[N:22]5[CH:21]=3)=[CH:7][NH:8]2)=[CH:4][CH:3]=1참가 물질
3
실험 절차
Beginning with 2-(6-fluoro-1H-indol-3-yl)acetamide and (4-hydroxymethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)oxoacetic acid methyl ester, the title compound was prepared essentially as described in Example 1.
출처 및 근거
- ORD 기록
- ord-54271e7ed7b04dd192a7b6964aff59a2
- 출처 데이터셋
- uspto-grants-2005_03