1-(4-Phenoxyphenyl)piperazine → 5-[4-(4-(4-Phenoxyphenyl)piperazin-1-yl)butyryl]2,3,4,5-tetrahydro-1,5-benzoxazepine

HRID 984

반응식

HRID 984 반응식
Cl[CH2:2][CH2:3][CH2:4][C:5]([N:7]1[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=2[O:11][CH2:10][CH2:9][CH2:8]1)=[O:6].[O:18]([C:25]1[CH:30]=[CH:29][C:28]([N:31]2[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]2)=[CH:27][CH:26]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[O:18]([C:25]1[CH:30]=[CH:29][C:28]([N:31]2[CH2:36][CH2:35][N:34]([CH2:2][CH2:3][CH2:4][C:5]([N:7]3[C:13]4[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=4[O:11][CH2:10][CH2:9][CH2:8]3)=[O:6])[CH2:33][CH2:32]2)=[CH:27][CH:26]=1)[C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1

참가 물질

3

반응물 2

HCID 30173561-(4-Phenoxyphenyl)piperazineHCID 196942505-(4-Chlorobutyryl)-2,3,4,5-tetrahydro-1,5-benzoxazepine

생성물 1

HCID 196942325-[4-(4-(4-Phenoxyphenyl)piperazin-1-yl)butyryl]2,3,4,5-tetrahydro-1,5-benzoxazepine

실험 절차

The compound (16) synthesized in Reference Example 16 and 1-(4-phenoxylphenyl)piperazine [DE 2631885] were used to produce the above compound in the same way as Example 1.

후처리

  1. customto produce the above compound in the same way as Example 1

출처 및 근거

ORD 기록
ord-e55b92dd5753463f9e20cccc10543c7b
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05723475

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