2-(6-fluoro-1H-indol-3-yl)acetamide → 3-(5-(methoxy)methyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(6-fluoro-1H-indol-3-yl)pyrrole-2,5-dione
반응식
CO[C:3](=[O:21])[C:4]([C:6]1[C:16]2=[C:17]3[C:12](=[CH:13][CH:14]=[CH:15]2)[CH2:11][CH:10]([CH2:18][O:19][CH3:20])[CH2:9][N:8]3[CH:7]=1)=O.[F:22][C:23]1[CH:31]=[C:30]2[C:26]([C:27]([CH2:32][C:33]([NH2:35])=[O:34])=[CH:28][NH:29]2)=[CH:25][CH:24]=1>>[CH3:20][O:19][CH2:18][CH:10]1[CH2:11][C:12]2[C:17]3=[C:16]([C:6]([C:4]4[C:3](=[O:21])[NH:35][C:33](=[O:34])[C:32]=4[C:27]4[C:26]5[C:30](=[CH:31][C:23]([F:22])=[CH:24][CH:25]=5)[NH:29][CH:28]=4)=[CH:7][N:8]3[CH2:9]1)[CH:15]=[CH:14][CH:13]=2참가 물질
3
실험 절차
Beginning with (5-methoxymethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)oxoacetic acid methyl ester and (6-fluoro-1H-indol-3-yl)acetamide, the title compound was prepared essentially as described in Example 1.
출처 및 근거
- ORD 기록
- ord-3deba3b1366f40ad8ee2ac38c32aba33
- 출처 데이터셋
- uspto-grants-2005_03