HCID 20765970, 화합물 → HCID 20765975, 화합물

반응식

[CH3:1][O:2][C:3](=[O:18])[CH2:4][CH:5]1[CH2:13][C:12]2[C:7](=[CH:8][CH:9]=[C:10]([S:14](Cl)(=O)=O)[CH:11]=2)[CH2:6]1.COC(=O)CC1CC2C(=CC=C(SCC3SC(C4C=CC(C(F)(F)F)=CC=4)=NC=3C)C=2)C1>>[CH3:1][O:2][C:3](=[O:18])[CH2:4][CH:5]1[CH2:13][C:12]2[C:7](=[CH:8][CH:9]=[C:10]([SH:14])[CH:11]=2)[CH2:6]1

참가 물질

반응물 2

HCID 20765970HCID 20765970, 화합물2회

HCID 85864988HCID 85864988, 화합물

생성물 1

HCID 20765975HCID 20765975, 화합물

실험 절차

Compound 2C was prepared according to the method of Example 1 utilizing compound 2B. The crude product was used immediately. Preparation of {5-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethylsulfanyl]-indan-2-yl}-acetic acid methyl ester (Compound 2D)

출처 및 근거

ORD 기록: ord-146524488d614be5835f1a1f434006ef
출처 데이터셋: uspto-grants-2005_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06867224B2

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