Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzylamine → N-[4-(Methylthio)phenyl]benzenemethanamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzylamine | HCID 7504 | — |
| 반응물 | 4-Bromothioanisole | HCID 66037 | — |
| 생성물 | N-[4-(Methylthio)phenyl]benzenemethanamine | HCID 9964622 | 88% |
반응 단계
Using the general procedure, 4-bromothioanisole (203 mg, 1.0 mmol) was coupled with benzylamine (164 μL, 1.5 mmol). Purification of the crude product by column chromatography on silica gel using hexane/ethyl acetate (15:1) as eluent afforded the desired product as a white solid (201 mg, 88% yield). Rf=0.4 (hexane/ethyl acetate=10:1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06867298B2 |
| 출처 데이터셋 | uspto-grants-2005_03 |
| ORD ID | ord-a5a87c535263438ca18bce494f1ecc2e |
| 출처 메모 | uspto-grants-2005_03 |