Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hexylamine → [2-(Hexylamino)phenyl]methanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hexylamine | HCID 8102 | — |
| 반응물 | 2-Bromobenzyl alcohol | HCID 72850 | — |
| 생성물 | [2-(Hexylamino)phenyl]methanol | HCID 15084054 | 81% |
반응 단계
Using the general procedure, 2-bromobenzyl alcohol (187 mg, 1.0 mmol) was coupled with n-hexylamine (198 μL, 1.5 mmol) at 90° C. for 22 h. Purification of the crude product by column chromatography on silica gel using hexane/ethyl acetate (6:1) as eluent afforded the desired product as a colorless liquid (168 mg, 81% yield). Rf=0.7 (hexane/ethyl acetate=2:1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06867298B2 |
| 출처 데이터셋 | uspto-grants-2005_03 |
| ORD ID | ord-d5ec20fddb934fe3adb416f27f404e0f |
| 출처 메모 | uspto-grants-2005_03 |