Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol → 3,4-Dihydroxythiophene-2,5-dicarboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 3,4-Dihydroxy-thiophene-2,5-dicarboxylic acid diethyl ester | HCID 245503 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3,4-Dihydroxythiophene-2,5-dicarboxylic acid | HCID 316269 | — |
반응 단계
EtOH (30 mL) was added to 2,5-dicarbethoxy-3,4-dihydroxythiophene (1 g). A solution of NaOH (4.0 g) in H2O (20 mL) was added and refluxed under N for 20 h. Upon cooling to ambient temperature the EtOH was removed by distillation and the residue was redissolved in H2O then acidified with 15% HClaq when a white ppt was obtained This product was collected by filtration and washed with cold H2O then crystallized from dilute MeOH to give colorless needles.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06869729B1 |
| 출처 데이터셋 | uspto-grants-2005_03 |
| ORD ID | ord-0e1c8a71196d4753a61e5b592f8c8adb |
| 출처 메모 | uspto-grants-2005_03 |