3-(2-Bromoethyl)-5-fluorobenzofuran → 4-(Aminomethyl)-1-[2-(5-fluoro-benzofuran-3-yl)ethyl]-4-piperidinol

반응식

[F:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([c:7]([CH2:10][CH2:11][N:12]3[CH2:13][CH2:14][C:15]([OH:18])([CH2:19][NH:20][C:21](=[O:22])[O:23][CH2:24][CH3:25])[CH2:16][CH2:17]3)[cH:8][o:9]2)[cH:26]1.[F:27][c:28]1[cH:29][cH:30][c:31]2[o:32][cH:33][c:34]([CH2:35][CH2:36][Br:37])[c:38]2[cH:39]1>>[F:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([c:7]([CH2:10][CH2:11][N:12]3[CH2:13][CH2:14][C:15]([OH:18])([CH2:19][NH2:20])[CH2:16][CH2:17]3)[cH:8][o:9]2)[cH:26]1

참가 물질

반응물 2

HCID 181842963-(2-Bromoethyl)-5-fluorobenzofuran

HCID 70198276ethyl N-{1-[2-(5-fluoro-benzofuran-3-yl)ethyl]-4-hydroxy-4-piperidylmethyl}carbamate

생성물 1

HCID 183513564-(Aminomethyl)-1-[2-(5-fluoro-benzofuran-3-yl)ethyl]-4-piperidinol

출처 및 근거

ORD 기록: ord-17a011d635744d3487fbfca13df3bcba
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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