참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Isopropanol | HCID 3776 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 반응물 | Benzenepropanal, alpha,alpha,3-trimethyl- | HCID 13797308 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | Majantol | HCID 175948 | — |
반응 단계
44 g of 2,2-dimethyl-3-(3-methylphenyl)-propionaldehyde (according to Example 3) were added in small portions under argon and at 20° C. to a pre-mix of 150 ml of isopropanol and 3.8 g of sodium borohydride. The entire mixture was stirred for 24 hours at 20° C. Excess sodium borohydride was then decomposed by the dropwise addition of 2N HCl. The reaction mixture was then taken up in 150 ml of diethyl ether and extracted with water, 2N NaOH and, again, with water.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04710316 |
|---|
| 출처 데이터셋 | uspto-grants-1987_12 |
|---|
| ORD ID | ord-c3daf21f1f544a39a01ecd90a322c1bf |
|---|
| 출처 메모 | uspto-grants-1987_12 |
|---|
