Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Enprofylline → 3-Propyl-6-thioxanthine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Enprofylline | HCID 1676 | — |
| 반응물 | Phosphorus sulfide (P2S5) | HCID 14817 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 3-Propyl-6-thioxanthine | HCID 14014540 | — |
반응 단계
A suspension of 9.32 g. (48 mM.) of 3-propylxanthine in 80 ml. of pyridine, was treated with 17.33 g. (78 mM.) of phosphorus pentasulfide in 80 ml. of pyridine, and worked up analogously to Example I. 8.9 g. of 3-propyl-6-thioxanthine was obtained. Recrystallization from methanol-acetone gave 7.4 g. (59% yield) of needles with a melting point of 249°-250° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04710503 |
| 출처 데이터셋 | uspto-grants-1987_12 |
| ORD ID | ord-d2a3177f855d42d6a0dcc040f2a3c249 |
| 출처 메모 | uspto-grants-1987_12 |