참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Imidazole | HCID 795 | — |
| 반응물 | Water | HCID 962 | — |
| 반응물 | o-Toluenesulfonyl chloride, 5-nitro- | HCID 8457 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 1-(5-Nitro-2-methyl-phenylsulfonyl)-imidazole | HCID 685057 | 63.6% |
반응 단계
2.36 g of 5-nitro-2-methyl-phenylsulfonyl chloride (0.01 mol) and 1.36 g of imidazole (0.02 mol) were dissolved in 15 ml of pyridine, and the mixture was stirred at 50° C. for 3 hours to react. After the reaction, the reaction mixture was poured into water, and extracted with chloroform. The chloroform layer was washed with water and dehydrated. Evaporation of chloroform gave 1.70 g of 1-(5-nitro-2-methyl-phenylsulfonyl)-imidazole of the m.p. 119°-120° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04710509 |
|---|
| 출처 데이터셋 | uspto-grants-1987_12 |
|---|
| ORD ID | ord-fcb44b4c21584b2e92d076268a6bba5c |
|---|
| 출처 메모 | uspto-grants-1987_12 |
|---|
