Water → Benzenebutanenitrile
반응식
Br[CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[C-]#[N:13].[Na+].O>C(O)C>[C:6]1([CH2:5][CH2:4][CH2:3][C:2]#[N:13])[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1참가 물질
5
실험 절차
A mixture of 1-bromo-4-phenylbutane (58.8 g, 0.24 mole) and sodium cyanide (25 g, 0.5 mole) in ethanol (300 ml)-water (100 ml) is heated at reflux with stirring for 5 hours. The resulting reaction mixture is concentrated in vacuo and extracted with ether. The ethereal extract is filtered and evaporated at reduced pressure to afford the title compound which is purified by distillation.
후처리
- temperatureis heated
- temperatureat reflux
- customThe resulting reaction mixture
- concentrationis concentrated in vacuo
- extractionextracted with ether
- extractionThe ethereal extract
- filtrationis filtered
- customevaporated at reduced pressure
출처 및 근거
- ORD 기록
- ord-9cb44be14b204593ab8d9f6cffb530e3
- 출처 데이터셋
- uspto-grants-1987_12
- 특허 번호
- US04710513
반응 노트
불러오는 중…