3-(5-Nitrofuran-2-yl)prop-2-enal → 3-(6-Methoxy-3-pyridyl)-2-propenoic acid [3-(5-nitro-2-furyl)-2-propen-1-ylidene]hydrazide

HRID 986223노트

반응식

HRID 986223 반응식
[CH3:1][O:2][C:3]1[N:8]=[CH:7][C:6]([CH:9]=[CH:10][C:11]([NH:13][NH2:14])=[O:12])=[CH:5][CH:4]=1.[N+:15]([C:18]1[O:22][C:21]([CH:23]=[CH:24][CH:25]=O)=[CH:20][CH:19]=1)([O-:17])=[O:16]>CO>[N+:15]([C:18]1[O:22][C:21]([CH:23]=[CH:24][CH:25]=[N:14][NH:13][C:11](=[O:12])[CH:10]=[CH:9][C:6]2[CH:7]=[N:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)=[CH:20][CH:19]=1)([O-:17])=[O:16]

참가 물질

4

반응물 2

HCID 158633-(5-Nitrofuran-2-yl)prop-2-enalHCID 704352203-(6-Methoxy-3-pyridyl)-2-propenoic acid hydrazide

생성물 1

HCID 542876343-(6-Methoxy-3-pyridyl)-2-propenoic acid [3-(5-nitro-2-furyl)-2-propen-1-ylidene]hydrazide

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

To a lukewarm solution of 0.85 g (4.4. mmol) of 3-(6-methoxy-3-pyridyl)-2-propenoic acid hydrazide in 50 ml of methanol, 0.75 g (4.5 mmol) of 3-(5-nitro-2-furyl)-2-propenal is added. A solid crystallizes slowly in the resulting homogenous solution. After the mixture has been stirred for several hours, these crystals are drained, washed with methanol and ether and dried under reduced pressure at 100° C. for 8 h.

후처리

  1. customA solid crystallizes slowly in the resulting homogenous solution
  2. washwashed with methanol and ether
  3. customdried under reduced pressure at 100° C. for 8 h.

출처 및 근거

ORD 기록
ord-66680e05d6804ff5bb58b7465d38ba45
출처 데이터셋
uspto-grants-1987_12
특허 번호
US04711892

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