Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 7-Thienylamino-1H-pyrazolo[4,3-b]pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Ethyl 7-thienylamino-1H-pyrazolo[4,3-b]pyridine-6-carboxylate | HCID 20156241 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 7-Thienylamino-1H-pyrazolo[4,3-b]pyridine | HCID 20156244 | — |
반응 단계
Ethyl 7-thienylamino-1H-pyrazolo[4,3-b]pyridine-6-carboxylate (0.600 g) was converted to the corresponding acid by heating under reflux with a 2% sodium hydroxide solution in ethanol (50 ml). The ethanol was removed under reduced pressure and the residue diluted with water (5 ml) and acidified to pH5 with dilute hydrochloric acid. The resulting acid was filtered off and dried, mp 255°-259° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04716160 |
| 출처 데이터셋 | uspto-grants-1987_12 |
| ORD ID | ord-795da91dd8ec4d3bba0d28a4380803d5 |
| 출처 메모 | uspto-grants-1987_12 |