Dimethylamine → HCID 21766691, 화합물

반응식

Br[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[N:9][CH:10]=2)[N:5]=[CH:4][CH:3]=1.[CH3:12][NH:13][CH3:14]>>[CH3:12][N:13]([CH3:14])[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[N:9][CH:10]=2)[N:5]=[CH:4][CH:3]=1

참가 물질

반응물 2

HCID 674Dimethylamine

HCID 125201424-BroMo-1,6-naphthyridine

생성물 1

HCID 21766691HCID 21766691, 화합물

실험 절차

Paudler et al., J. Heterocyclic Chem. 2 (4), 393-8 (1965), show the synthesis and NMR spectra of various 4-substituted-1,6-naphthyridines, for example, the reaction of 4-hydroxy-1,6-naphthyridine with POBr3 or POCl3 to obtain 4-bromo-1,6-naphthyridine or 4-chloro-1,6-naphthyridine, respectively. Also shown is the reaction of 4-bromo-1,6-naphthyridine with dimethylamine to produce 4-dimethylamino-1,6-naphthyridine and the reaction 4-chloro-1,6-naphthyridine with piperidine or hydrazine to produce 4-(1-piperidinyl)-1,6-naphthyridine or 4-hydrazino-1,6-naphthyridine, respectively.

출처 및 근거

ORD 기록: ord-14031932ca9b4a2aabc89575e33b5ed5
출처 데이터셋: uspto-grants-1987_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04716170

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