Perfluoro-2-butanone → HCID 131723633, 화합물

HRID 986885노트

반응식

HRID 986885 반응식
[F:1][C:2]([F:13])([F:12])[C:3](=[O:11])[C:4]([F:10])([F:9])[C:5]([F:8])([F:7])[F:6]>N1C=CC=CC=1>[C:2]([C:3]([C:4]([C:5]([F:6])([F:7])[F:8])([F:9])[F:10])=[O:11])([F:13])([F:12])[F:1].[F:1][C:2]([F:12])([F:13])[C:3](=[O:11])[C:4]([F:10])([F:9])[C:5]([F:8])([F:7])[F:6]

참가 물질

3

반응물 1

HCID 3429852Perfluoro-2-butanone

생성물 1

HCID 131723633HCID 131723633, 화합물

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

1341 g of sec-butyl acetate was fluorinated using essentially the same procedure as described in U.S. Pat. No. 5,488,142 (Fall et al.). The resulting perfluorinated ester (688 g) was isolated from the reaction mixture by fractionation. The ester was then decomposed according to the method described by Moore in U.S. Pat. No. 5,466,877 wherein the ester was added dropwise to a 1-liter, 3-neck flask equipped with a magnetic stirrer, dry ice condenser and temperature probe containing 0.5 mL of pyridine. The pot temperature was maintained at about −10° C., during which time the conversion to the ketone occurred. The gaseous ketone product was fractionated to give 435 g. of 1,1,1,3,3,4,4,4-octafluoro-butan-2-one, having a boiling point of 0° C., with purity of 99.7% as determined by gas chromatography and mass spectroscopy.

후처리

  1. customequipped with a magnetic stirrer, dry ice condenser
  2. customto give 435 g

출처 및 근거

ORD 기록
ord-7f7615717e9244ef916e285590d6f7f7
출처 데이터셋
uspto-grants-2003_10
특허 번호
US06630075B2

반응 노트

불러오는 중…