2-Hydrazinopyrazine → 7H-Pyrrolo(2,3-d)pyrimidine

반응식

[NH:1]([C:3]1[CH:8]=[CH:7][N:6]=[CH:5][N:4]=1)N.[NH:9]([C:11]1[N:12]=[N:13][CH:14]=[CH:15][CH:16]=1)N.[NH:17]([C:19]1[CH:24]=[N:23][CH:22]=[CH:21][N:20]=1)N>>[N:4]1[C:3]2[NH:1][CH:11]=[CH:16][C:8]=2[CH:7]=[N:6][CH:5]=1.[N:12]1[C:11]2[NH:9][CH:19]=[CH:24][C:16]=2[CH:15]=[CH:14][N:13]=1.[N:23]1[CH:22]=[CH:21][N:20]=[C:19]2[NH:17][CH:3]=[CH:8][C:24]=12

참가 물질

반응물 3

HCID 14878232-Hydrazinopyrazine

HCID 122285544-Hydrazinopyrimidine

HCID 122953913-Hydrazinopyridazine

생성물 3

HCID 2615917H-Pyrrolo(2,3-d)pyrimidine

HCID 53708035H-Pyrrolo[2,3-b]pyrazine

HCID 115137407H-Pyrrolo(2,3-c)pyridazine

실험 절차

Substituting 2-hydrazinopyridine 51 with 4-hydrazinopyrimidine, 3-hydrazinopyridazine or 2-hydrazinopyrazine and following the procedure described above gives 7H-pyrrolo[2,3-d]pyrimidine, 7H-pyrrolo[2,3-c]pyridazine or 5H-pyrrolo[2,3-b]pyrazine respectively.