Methyl 3-(4-hydroxyphenyl)-2-methoxypropanoate → 3-{4-[2-(4-Methanesulfonyloxyphenyl)ethoxy]-phenyl}-2-methoxypropanoic acid methyl ester
반응식
[CH3:1][O:2][C:3](=[O:15])[CH:4]([O:13][CH3:14])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][CH:7]=1.[CH3:16][S:17]([O:20][C:21]1[CH:26]=[CH:25][C:24]([CH2:27][CH2:28]CS([O-])(=O)=O)=[CH:23][CH:22]=1)(=[O:19])=[O:18]>>[CH3:1][O:2][C:3](=[O:15])[CH:4]([O:13][CH3:14])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH2:28][CH2:27][C:24]2[CH:23]=[CH:22][C:21]([O:20][S:17]([CH3:16])(=[O:18])=[O:19])=[CH:26][CH:25]=2)=[CH:8][CH:7]=1참가 물질
3
실험 절차
3-(4-Hydroxyphenyl)-2-methoxypropanoic acid methyl ester was alkylated with 2-(4-methanesulfonyloxyphenyl)ethylmethanesulfonate (described in Example 1a) using the same method as in Example 1 (b) to give 3-{4-[2-(4-methanesulfonyloxyphenyl)ethoxy]-phenyl}-2-methoxypropanoic acid methyl ester.
출처 및 근거
- ORD 기록
- ord-38e5ab78183e404c84e5ae8c0983f2ae
- 출처 데이터셋
- uspto-grants-2003_10