Sulfuric Acid → Ethyl 3-(3-bromo-4-hydroxyphenyl)acrylate

HRID 988032노트

반응식

HRID 988032 반응식
[Br:1][C:2]1[CH:3]=[C:4]([CH:12]=[CH:13][C:14]([O:16][CH2:17][CH3:18])=[O:15])[CH:5]=[CH:6][C:7]=1[O:8]COC.S(=O)(=O)(O)O>>[Br:1][C:2]1[CH:3]=[C:4]([CH:12]=[CH:13][C:14]([O:16][CH2:17][CH3:18])=[O:15])[CH:5]=[CH:6][C:7]=1[OH:8]

참가 물질

3

반응물 2

HCID 1118Sulfuric AcidHCID 69794021Ethyl 3-(3-bromo-4-methoxymethoxyphenyl)acrylate

생성물 1

HCID 69793988Ethyl 3-(3-bromo-4-hydroxyphenyl)acrylate수율 70.9%

실험 절차

In a manner similar to that of Example 2(g), by reaction of 10.1 g (20.3 mmol) of ethyl 3-(3-bromo-4-methoxymethoxyphenyl)acrylate obtained in Example 2(c) with 5.4 ml (102 mmol) of 98% sulfuric acid, 3.9 g of ethyl 3-(3-bromo-4-hydroxyphenyl)acrylate (49%) were obtained in the form of a white powder having a melting point of 112°-3° C.

출처 및 근거

ORD 기록
ord-79bf1acec2b641ea82b5cb969ff4c799
출처 데이터셋
uspto-grants-2003_10
특허 번호
US06632963B1

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