3-(2-Formyl-5-methyl-1H-pyrrol-3-yl)propanoic acid → HCID 69584070, 화합물

반응식

[NH:1]1[CH2:6][CH2:5][CH:4]([C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH2:9][C:10](=[O:16])[NH:11]3)[CH2:3][CH2:2]1.[CH:17]([C:19]1[NH:20][C:21]([CH3:29])=[CH:22][C:23]=1[CH2:24][CH2:25][C:26]([OH:28])=[O:27])=O>>[CH3:29][C:21]1[NH:20][C:19]([CH:17]=[C:9]2[C:8]3[C:12](=[CH:13][CH:14]=[CH:15][C:7]=3[CH:4]3[CH2:3][CH2:2][NH:1][CH2:6][CH2:5]3)[NH:11][C:10]2=[O:16])=[C:23]([CH2:24][CH2:25][C:26]([OH:28])=[O:27])[CH:22]=1

참가 물질

반응물 2

HCID 221353943-(2-Formyl-5-methyl-1H-pyrrol-3-yl)propanoic acid

HCID 221353964-(Piperidin-4-yl)indolin-2-one

생성물 1

HCID 69584070HCID 69584070, 화합물

실험 절차

4-Piperidin-4-yl-1,3-dihydroindol-2-one (45 mg, 0.2 mmol) was condensed with 3-(2-formyl-5-methyl-1H-pyrrol-3-yl)-propionic acid (42 mg, 0.23 mmol) to give the title compound.

출처 및 근거

ORD 기록: ord-3c2c2c58e4034bb68da186df4f228b2e
출처 데이터셋: uspto-grants-2003_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06635640B2

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