Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 4-Phenylcyclohexan-1-amine--hydrogen chloride (1/1)
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 4-Phenylcyclohexanone oxime | HCID 343882 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4-Phenylcyclohexan-1-amine--hydrogen chloride (1/1) | HCID 201281 | 100% |
반응 단계
A mixture of 1-(hydroxyimino)-4-phenylcyclohexane (17.4 mmol) and Raney Nickel (300 mg) in ethanol was hydrogenated (90 psi) at 50° C. for 40 hours. The mixture was filtered through a pad of Celite, washed with MeOH, and concentrated. The residue was dissolved in MeOH, treated with HCl (4 N in dioxane, 20 mmol), and concentrated to give 4-phenylcyclohexylamine hydrochloride (100%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06638927B2 |
| 출처 데이터셋 | uspto-grants-2003_10 |
| ORD ID | ord-4b8b58b12c5641d1a30f2a7d77ccf4b7 |
| 출처 메모 | uspto-grants-2003_10 |