2-Bromo-N-phenylacetamide → N-phenyl-4-[4-(4-fluorophenyl)methylphenyl]-1-piperidinacetamide

HRID 989

반응식

HRID 989 반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]2[CH:14]=[CH:13][C:12]([CH:15]3[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]3)=[CH:11][CH:10]=2)=[CH:4][CH:3]=1.[C:21]1([NH:27][C:28](=[O:31])[CH2:29]Br)[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[C:21]1([NH:27][C:28](=[O:31])[CH2:29][N:18]2[CH2:17][CH2:16][CH:15]([C:12]3[CH:13]=[CH:14][C:9]([CH2:8][C:5]4[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=4)=[CH:10][CH:11]=3)[CH2:20][CH2:19]2)[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

참가 물질

3

반응물 2

HCID 948182-Bromo-N-phenylacetamideHCID 154621204-[4-(4-Fluorophenyl)methylphenyl]piperidine

생성물 1

HCID 19694263N-phenyl-4-[4-(4-fluorophenyl)methylphenyl]-1-piperidinacetamide

실험 절차

The compound (7) synthesized in Reference Example 7 and the compound (23) synthesized in Reference Example 23 were used to produce the above compound in the same way as Example 1.

후처리

  1. customto produce the above compound in the same way as Example 1

출처 및 근거

ORD 기록
ord-0dbe0dca9fae46829877e914cdfc371e
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05723475

연결된 노트

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