Tetrahydrofuran → HCID 18005526, 화합물

HRID 989263

반응식

HRID 989263 반응식
C([Si](C)(C)O[C:7]1[CH2:13][CH2:12][CH2:11][CH2:10][C:9](=[CH:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[CH3:21])[CH:8]=1)(C)(C)C.C1C[O:27]CC1>>[CH3:21][C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=1[CH2:14][C:9]1[C:8](=[O:27])[CH2:7][CH2:13][CH2:12][CH2:11][CH:10]=1

참가 물질

3

반응물 2

HCID 8028Tetrahydrofuran2회HCID 69965728tert-Butyl(dimethyl){[3-(2-methylbenzylidene)-1-cyclohepten-1-yl]oxy}silane

생성물 1

HCID 18005526HCID 18005526, 화합물

실험 절차

A solution of n-tetra-n-butylammonium fluoride (1M) in THF (1.35 mmol) is added using a syringe to a solution of the compound obtained in Step A (1.34 mmol) in 15 ml of anhydrous THF at 0° C., and the whole is stirred at that temperature for 1 hour 30 minutes. The reaction mixture is then concentrated to dryness and deposited directly over a column of silica gel (heptane/AcOEt 9/1) to yield the title product.

후처리

  1. customat 0° C.
  2. concentrationThe reaction mixture is then concentrated to dryness

출처 및 근거

ORD 기록
ord-8ab77105869e4e05b0462a40eb1a982f
출처 데이터셋
uspto-grants-2003_10
특허 번호
US06638962B2

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