Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Methyl-2-butanol → HCID 178467923, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Methyl-2-butanol | HCID 6405 | — |
| 반응물 | 4-Amino-1-butanol | HCID 25868 | — |
| 반응물 | Chloride 2-chloropyridinium 1-oxide | HCID 88478 | — |
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 생성물 | HCID 178467923 | HCID 178467923 | 63.4% |
반응 단계
A mixture of 4-amino-1-butanol (2.0 mL, 21.7 mmole), 2-chloropyridine-N-oxide hydrochloride (3.00 g, g, 18.0 mmole), NaHCO3 (7.56 g, 90.0 mmole), and tert-amyl alcohol (22 mL) was heated at reflux. After 24 hr, the mixture was cooled and filtered, then the filtrate was concentrated under reduced pressure. Silica gel chromatography (10% MeOH/CHCl3) gave the title compound (2.08 g, 63%) as a yellow solid: MS (ES) m/e 183 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06458814B1 |
| 출처 데이터셋 | uspto-grants-2002_10 |
| ORD ID | ord-725a001c5e3b47b2b930de63657ef8c2 |
| 출처 메모 | uspto-grants-2002_10 |