4-(4-Phenoxyphenyl)piperidine → N-(2,6-diisopropylphenyl)-4-(4-phenoxyphenyl)-1-piperidinacetamide

HRID 990

반응식

HRID 990 반응식
[O:1]([C:8]1[CH:13]=[CH:12][C:11]([CH:14]2[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]2)=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:20]([C:23]1[CH:28]=[CH:27][CH:26]=[C:25]([CH:29]([CH3:31])[CH3:30])[C:24]=1[NH:32][C:33](=[O:36])[CH2:34]Br)([CH3:22])[CH3:21]>>[CH:20]([C:23]1[CH:28]=[CH:27][CH:26]=[C:25]([CH:29]([CH3:30])[CH3:31])[C:24]=1[NH:32][C:33](=[O:36])[CH2:34][N:17]1[CH2:18][CH2:19][CH:14]([C:11]2[CH:12]=[CH:13][C:8]([O:1][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)=[CH:9][CH:10]=2)[CH2:15][CH2:16]1)([CH3:21])[CH3:22]

참가 물질

3

반응물 2

HCID 110759844-(4-Phenoxyphenyl)piperidineHCID 12149064Acetamide, N-[2,6-bis(1-methylethyl)phenyl]-2-bromo-

생성물 1

HCID 19694264N-(2,6-diisopropylphenyl)-4-(4-phenoxyphenyl)-1-piperidinacetamide

실험 절차

The compound (4) synthesized in Reference Example 4 and the compound (24) synthesized in Reference Example 24 were used to produce the above compound in the same way as Example 1.

후처리

  1. customto produce the above compound in the same way as Example 1

출처 및 근거

ORD 기록
ord-d49e044d91ba41819787fce94b25dafb
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05723475

연결된 노트

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