HCID 10892675, 화합물 → HCID 10115750, 화합물

반응식

[F:1][C:2]([F:23])([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=1)[CH2:3][NH:4][C:5]1[C:6](=[O:16])[N:7]([CH2:12][C:13]([OH:15])=O)[C:8]([CH3:11])=[CH:9][N:10]=1.[F:24][C:25]([F:34])([C:28]1[CH:33]=[CH:32][N:31]=[CH:30][CH:29]=1)[CH2:26][NH2:27]>>[F:34][C:25]([F:24])([C:28]1[CH:33]=[CH:32][N:31]=[CH:30][CH:29]=1)[CH2:26][NH:27][C:13](=[O:15])[CH2:12][N:7]1[C:8]([CH3:11])=[CH:9][N:10]=[C:5]([NH:4][CH2:3][C:2]([F:1])([F:23])[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=2)[C:6]1=[O:16]

참가 물질

반응물 2

HCID 10892675HCID 10892675, 화합물

HCID 18416311HCID 18416311, 화합물

생성물 1

HCID 10115750HCID 10115750, 화합물

실험 절차

7-1 was prepared from [3-(2,2-difluoro-2-pyridin-2-ylethylamino)-6-methyl-2-oxo-2H-pyrazin-1-yl]-acetic acid and 2,2-difluoro-2-(4-pyridyl)ethyl amine essentially according to the procedure of Example 1, Step K. Mass Spectrum: Found: (M+1) 465.2.

출처 및 근거

ORD 기록: ord-1cd21778d6014c8bacdf7ada9c617664
출처 데이터셋: uspto-grants-2002_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06462050B1

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