Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Hydroxide → 1,3-Diphenyl-2-propyn-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | alpha-Bromochalcone | HCID 5383396 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Propan-2-one--water (1/1) | HCID 18366337 | — |
| 생성물 | 1,3-Diphenyl-2-propyn-1-one | HCID 97637 | — |
반응 단계
Potassium hydroxide (3.48 mmol), dissolved in water (0.87 M (4.0 ml)), is added over about 30 minutes to a refluxing solution of the alpha-bromochalcone (3.48 mmol) in 0.35 M of 1:1 water/acetone (5 ml each). After 20 minutes of further refluxing, the solution is cooled and diluted with water. The water is extracted with ether, which is dried with MgSO4 and evaporated. Chromatography on silica gel yielded 1,3-diphenylpropynone and its derivatives.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06462075B1 |
| 출처 데이터셋 | uspto-grants-2002_10 |
| ORD ID | ord-a0b061284c2142e98e2b0253dcf35b88 |
| 출처 메모 | uspto-grants-2002_10 |