Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bis(2-chloroethyl)ethylamine → 4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-ethyl-piperidine-4-carboxylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bis(2-chloroethyl)ethylamine | HCID 10848 | — |
| 반응물 | [4-(4-Chloro-phenoxy)-benzenesulfonyl]-acetic acid ethyl ester | HCID 11121795 | — |
| 생성물 | 4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-ethyl-piperidine-4-carboxylic acid ethyl ester | HCID 11762171 | — |
반응 단계
4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-ethyl-piperidine-4-carboxylic acid ethyl ester was prepared according to the general method outlined in example 83 starting from [4-(4-chloro-phenoxy)-benzenesulfonyl]-acetic acid ethyl ester (4 g, 11.3 mmol) and ethyl-bis-(2-chloro-ethyl)-amine (2.32 g, 16.9 mmol). Yield 3.36 g (66%); brown oil; MS: 452.0 (M+H)+
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06462073B2 |
| 출처 데이터셋 | uspto-grants-2002_10 |
| ORD ID | ord-f2a7e33cade349aaab13bc4baa8edcaf |
| 출처 메모 | uspto-grants-2002_10 |