5-Ethyl-1,3,4-oxadiazol-2-amine → N-(5-Ethyl-[1,3,4]oxadiazol-2-yl)-2,2-diphenyl-acetamide

반응식

CC1C=[C:5](C)[N:4]([C:8](=[O:22])[CH:9]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)N=1.[CH2:23]([C:25]1[O:29]C(N)=[N:27][N:26]=1)[CH3:24]>>[CH2:23]([C:25]1[O:29][C:5]([NH:4][C:8](=[O:22])[CH:9]([C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=2)[C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)=[N:27][N:26]=1)[CH3:24]

참가 물질

반응물 2

HCID 3434875-Ethyl-1,3,4-oxadiazol-2-amine

HCID 7743981-(3,5-Dimethylpyrazol-1-yl)-2,2-diphenylethanone

생성물 1

HCID 22661073N-(5-Ethyl-[1,3,4]oxadiazol-2-yl)-2,2-diphenyl-acetamide

실험 절차

The title compound, white solid, m.p. 123-125° C. and MS: m/e=308.2 (M+H+) was prepared in accordance with the general method of example 48a from 1-(3,5-dimethyl-pyrazol-1-yl)-2,2-diphenyl-ethanone and 5-ethyl-[1,3,4]oxadiazol-2-ylamine.

출처 및 근거

ORD 기록: ord-bf0f6cd2ae1d4bc696d6615c4da174ea
출처 데이터셋: uspto-grants-2002_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06462198B1

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